The EGR2 Polyclonal Antibody (CAB15053) is a valuable tool for researchers studying the EGR2 protein, which plays a crucial role in regulating gene expression and cell growth. This antibody is raised in rabbits and has been validated for use in Western blot applications, making it ideal for detecting and analyzing EGR2 protein levels in a variety of cell types.EGR2, also known as early growth response protein 2, is involved in various cellular processes, including differentiation, proliferation, and apoptosis.
Dysregulation of EGR2 has been linked to diseases such as cancer, neurological disorders, and immune disorders, making it a promising target for further research and therapeutic development.With its high reactivity with human samples, the EGR2 Polyclonal Antibody is a powerful tool for investigating the role of EGR2 in different biological contexts. Its specificity and reliability make it a valuable asset for researchers studying gene regulation, cell signaling, and disease mechanisms.
Product Name:
EGR2 Rabbit Polyclonal Antibody
SKU:
CAB15053
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human EGR2 (NP_000390.2).
The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1959
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse kidney, using EGR2 Rabbit pAb (CAB15053) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
