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EGFR Monoclonal Antibody [PAT2H8AT] (CPAB0278)

SKU:
CPAB0278
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT2H8AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

EGFR Monoclonal Antibody [PAT2H8AT] (CPAB0278)

The EGFR Antibody (PAT2H8AT) is a polyclonal antibody designed for research involving the epidermal growth factor receptor (EGFR), a cell surface protein implicated in regulating cell growth and proliferation. The antibody, derived from rabbit host, is highly reactive with human samples and is validated for use in various applications such as Western blot, immunohistochemistry, and flow cytometry.EGFR, also known as ErbB-1 or HER1, is a crucial signaling molecule involved in various cellular processes, including cell survival, differentiation, and proliferation. Dysregulation of EGFR signaling has been linked to cancer development, making it an important target for cancer research and therapy development.

By detecting and studying EGFR protein expression and localization in different cell types, this antibody helps researchers gain insights into EGFR-mediated signaling pathways and its role in cancer progression.Understanding the molecular mechanisms of EGFR activity is essential for developing targeted therapies that can disrupt aberrant EGFR signaling in cancer cells. With its high specificity and sensitivity, the EGFR Antibody (PAT2H8AT) is a valuable tool for advancing research in oncology and personalized medicine.

Product Name:EGFR Antibody (PAT2H8AT)
Product Sku:CPAB0278
Size:5μg
Host Species:Mouse
Immunogen:Anti-human EGFR mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human EGFR amino acids 424-65 purified from Ecoli.
Clone:PAT2H8AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:EGFR antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:Epidermal growth factor receptor or EGFR or Erb-1 is a membranal protein that acts as a receptor for the extracellular EGF proteins family. This protein is a part of a family of receptors called ErbB family which are all tyrosine kinases receptors. Mutations in the gene of this receptors can cause cancer.
Synonyms:ERBB, ERBB1, Epidermal growth factor receptor, HER1, PIG61, epidermal growth factor receptor, Urogastrone, Proto-oncogene c-ErbB-1, Oncogene ERBB, Cell proliferation inducing protein 61, Cell growth inhibiting protein 40, Avian erythroblastic leukemia viral (verbb) oncogene homolog.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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