The EGF Polyclonal Antibody (CAB13615) is a valuable tool for researchers studying epidermal growth factor (EGF) signaling pathways and their role in various cellular processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the EGF protein, this antibody allows for precise detection and analysis of EGF expression in a variety of cell types.EGF is a crucial growth factor that plays a key role in regulating cell proliferation, differentiation, and survival. Dysregulation of the EGF signaling pathway has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
By studying the expression and activity of EGF, researchers can gain valuable insights into disease mechanisms and potentially identify new therapeutic targets.With its high reactivity and specificity, the EGF Polyclonal Antibody (CAB13615) is an essential tool for researchers interested in unraveling the complex biology of EGF and its impact on human health. By enabling accurate detection and quantification of EGF levels, this antibody facilitates precise experiments and data analysis in the fields of molecular biology, cell biology, and oncology.
Product Name:
EGF Rabbit Polyclonal Antibody
SKU:
CAB13615
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 851-950 of human EGF (NP_001954.2).
This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Purification Method:
Affinity purification
Gene ID:
1950
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat skeletal muscle, using EGF Rabbit pAb (CAB13615) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
