EFNA4 Antibody (PACO13442)
- SKU:
- PACO13442
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
EFNA4 Antibody (PACO13442)
The EFNA4 Polyclonal Antibody (PAC013442) is a valuable tool for researchers studying EFNA4, a cell surface protein involved in cell adhesion and signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the EFNA4 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an ideal choice for investigations in the fields of cell biology and neuroscience.EFNA4, also known as ephrin-A4, is a member of the Eph receptor tyrosine kinase family and is known to play a crucial role in axon guidance during development.
Its involvement in cell-cell communication and regulation of cell migration makes EFNA4 a target of interest in research related to neurological disorders and cancer metastasis. By understanding the function and expression of EFNA4, researchers can gain insights into various biological processes and potentially identify new therapeutic targets for disease intervention.
| Antibody Name: | EFNA4 Antibody (PACO13442) |
| Antibody SKU: | PACO13442 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human EFNA4-Specific |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | ephrin-A4;EFNA4;EFL4;EPLG4;LERK4;MGC125826 ;Ephrin A4; LERK-4 |
| UniProt Protein Function: | EFNA4: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils. Belongs to the ephrin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Ligand, receptor tyrosine kinase; Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 1q21-q22 Cellular Component: extracellular region; integral to plasma membrane; plasma membrane Molecular Function:ephrin receptor binding; protein binding; transmembrane-ephrin receptor activity Biological Process: axon guidance; cell-cell signaling; ephrin receptor signaling pathway |
| NCBI Summary: | This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin. Three transcript variants that encode distinct proteins have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P52798 |
| NCBI GenInfo Identifier: | 3821237 |
| NCBI Gene ID: | 1945 |
| NCBI Accession: | CAA06993.1 |
| UniProt Secondary Accession: | P52798,O95457, Q5SR71, Q6FI57, C9JHJ8, G3XAK2, |
| UniProt Related Accession: | P52798 |
| Molecular Weight: | 22,584 Da |
| NCBI Full Name: | ephrin-A4 |
| NCBI Synonym Full Names: | ephrin-A4 |
| NCBI Official Symbol: | EFNA4Â Â |
| NCBI Official Synonym Symbols: | EFL4; EPLG4; LERK4Â Â |
| NCBI Protein Information: | ephrin-A4 |
| UniProt Protein Name: | Ephrin-A4 |
| UniProt Synonym Protein Names: | EPH-related receptor tyrosine kinase ligand 4; LERK-4 |
| Protein Family: | Ephrin |
| UniProt Gene Name: | EFNA4Â Â |
| UniProt Entry Name: | EFNA4_HUMAN |
Related Products
EFNA4 Antibody (PACO00768)
Human EFNA4 / Ephrin A4 ELISA Kit
EFNA4 Colorimetric Cell-Based ELISA Kit
Human Ephrin A4 (EFNA4) ELISA Kit
Mouse Efna4(Ephrin-A4) ELISA Kit
