The EFHC1 Polyclonal Antibody (CAB8002) is a valuable tool for researchers studying EFHC1, a protein associated with epilepsy and other neurological disorders. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting.EFHC1 is known to play a role in neuronal development and function, and mutations in the EFHC1 gene have been linked to several types of epilepsy. By targeting EFHC1 with this antibody, researchers can detect and analyze the protein in different cell types, shedding light on its function and potential implications for neurological disorders.
With its high reactivity and specificity, the EFHC1 Polyclonal Antibody is an essential tool for investigations into the mechanisms underlying epilepsy and other neurological conditions. This antibody can provide valuable insights into the role of EFHC1 in the brain, paving the way for the development of targeted therapies for individuals affected by these disorders.
Product Name:
EFHC1 Rabbit Polyclonal Antibody
SKU:
CAB8002
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 391-640 of human EFHC1 (NP_060570.2).
Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle.
Calculated MW:
74kDa
Observed MW:
74kDa
This gene encodes an EF-hand-containing calcium binding protein. The encoded protein likely plays a role in calcium homeostasis. Mutations in this gene have been associated with susceptibility to juvenile myoclonic epilepsy and juvenile absence epilepsy. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
114327
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using EFHC1 antibody (CAB8002) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
