The EEF1A1 Polyclonal Antibody (CAB17857) is a valuable tool for research involving EEF1A1, a protein that plays a critical role in protein synthesis and regulation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the EEF1A1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and cancer research.EEF1A1 is a versatile protein involved in the elongation phase of protein synthesis and has been linked to various cellular processes, including cell proliferation, apoptosis, and cytoskeletal organization.
Understanding the function and regulation of EEF1A1 is essential for uncovering its role in diseases such as cancer, neurodegenerative disorders, and developmental abnormalities. By targeting EEF1A1 with this polyclonal antibody, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.
Product Name:
eEF1A1 Rabbit Polyclonal Antibody
SKU:
CAB17857
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 301-400 of human eEF1A1 (NP_001393.1).
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes.
Purification Method:
Affinity purification
Gene ID:
1915
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using eEF1A1 Rabbit pAb (CAB17857) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
