null

EEF1A1/EEF1A2/EEF1A1P5 Antibody (PACO02169)

SKU:
PACO02169
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$323
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

EEF1A1/EEF1A2/EEF1A1P5 Antibody (PACO02169)

The EEF1A1/EEF1A2/EEF1A1P5 Antibody (PACO02169) is a highly specific and reliable tool for researchers studying translation elongation factor proteins EEF1A1, EEF1A2, and EEF1A1P5. These proteins are essential for protein synthesis and play crucial roles in cell growth, differentiation, and survival.This polyclonal antibody, raised in rabbits, shows high affinity and specificity for human samples and has been validated for use in Western blot applications. It binds specifically to EEF1A1, EEF1A2, and EEF1A1P5 proteins, enabling researchers to detect and analyze these proteins in various cell types.

This makes it an ideal tool for studies in molecular biology, cell biology, and cancer research.The EEF1A1/EEF1A2/EEF1A1P5 Antibody (PACO02169) is a valuable asset for researchers seeking to unravel the intricate mechanisms of protein synthesis and its regulation. Its use can contribute to a better understanding of cellular processes and may lead to the discovery of new therapeutic targets in diseases related to dysregulated protein synthesis, such as cancer and neurodegenerative disorders.

Antibody Name:EEF1A1/EEF1A2/EEF1A1P5 Antibody
Antibody SKU:PACO02169
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:WB:1:500-1:2000
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from the N-terminal region of human EF-1 alpha1/2.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:EEF1A1; EEF1A; EF1A; LENG7; Elongation factor 1-alpha 1; EF-1-alpha-1; Elongation factor Tu; EF-Tu; Eukaryotic elongation factor 1 A-1; eEF1A-1; Leukocyte receptor cluster member 7; EEF1A2; EEF1AL; STN; Elongation factor 1-alpha 2; EF-1-alpha-2; Eukaryoti
UniProt Protein Function:EEF1A1: an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
UniProt Protein Details:

Protein type:Nucleolus; Translation; Translation elongation

Chromosomal Location of Human Ortholog: 6q14.1

Cellular Component: extracellular space; cortical actin cytoskeleton; eukaryotic translation elongation factor 1 complex; membrane; cytoplasm; nucleolus; nucleus; cytosol

Molecular Function:GTPase activity; protein binding; GTP binding; protein kinase binding; translation elongation factor activity; tRNA binding

Biological Process: cellular protein metabolic process; translational elongation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; translation; gene expression

NCBI Summary:This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008]
UniProt Code:P68104
NCBI GenInfo Identifier:55584035
NCBI Gene ID:1915
NCBI Accession:P68104.1
UniProt Secondary Accession:P68104,P04719, P04720, Q6IQ15,
UniProt Related Accession:P68104
Molecular Weight:
NCBI Full Name:Elongation factor 1-alpha 1
NCBI Synonym Full Names:eukaryotic translation elongation factor 1 alpha 1
NCBI Official Symbol:EEF1A1  
NCBI Official Synonym Symbols:CCS3; EF1A; PTI1; CCS-3; EE1A1; EEF-1; EEF1A; EF-Tu; LENG7; eEF1A-1; GRAF-1EF; HNGC:16303  
NCBI Protein Information:elongation factor 1-alpha 1; EF-1-alpha-1; EF1a-like protein; CTCL tumor antigen; elongation factor Tu; cervical cancer suppressor 3; elongation factor 1 alpha subunit; prostate tumor-inducing protein 1; eukaryotic elongation factor 1 A-1; leukocyte receptor cluster member 7; leukocyte receptor cluster (LRC) member 7; translation elongation factor 1 alpha 1-like 14; glucocorticoid receptor AF-1 specific elongation factor; eukaryotic translation elongation factor 1 alpha 1-like 14
UniProt Protein Name:Elongation factor 1-alpha 1
UniProt Synonym Protein Names:Elongation factor Tu; EF-Tu; Eukaryotic elongation factor 1 A-1; eEF1A-1; Leukocyte receptor cluster member 7
UniProt Gene Name:EEF1A1  
UniProt Entry Name:EF1A1_HUMAN

Related Products