EED Rabbit Polyclonal Antibody (CAB5371)
- SKU:
- CAB5371
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | EED Rabbit Polyclonal Antibody |
SKU: | CAB5371 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-400 of human EED (NP_694536.1). |
Sequence: | MSER EVST APAG TDMP AAKK QKLS SDEN SNPD LSGD ENDD AVSI ESGT NTER PDTP TNTP NAPG RKSW GKGK WKSK KCKY SFKC VNSL KEDH NQPL FGVQ FNWH SKEG DPLV FATV GSNR VTLY ECHS QGEI RLLQ SYVD ADAD ENFY TCAW TYDS NTSH PLLA VAGS RGII RIIN PITM QCIK HYVG HGNA INEL KFHP RDPN LLLS VSKD HALR LWNI QTDT LVAI FGGV EGHR DEVL SADY DLLG EKIM SCGM DHSL KLWR INSK RMMN AIKE SYDY NPNK TNRP FISQ KIHF PDFS TRDI HRNY VDCV RWLG DLIL SKSC ENAI VCWK PGKM EDDI DKIK PSES NVTI LGRF DYSQ CDIW YMRF SMDF WQKM LALG NQVG KLYV WDLE VEDP HKAK |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsIF/ICC,1:50 - 1:200 |
Synonyms: | HEED; COGIS; WAIT1; EED |
Positive Sample: | HeLa,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 50kDa |
Observed MW: | 50-70kDa |
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8726 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |