The EED Polyclonal Antibody (CAB12773) is a valuable tool for researchers studying the EED protein, which is involved in epigenetic regulation and gene expression. This antibody, produced in rabbits, shows high reactivity with human samples and is suitable for use in various applications including Western blot, immunofluorescence, and immunohistochemistry.EED is a key component of the Polycomb Repressive Complex 2 (PRC2), which plays a critical role in gene silencing and chromatin remodeling. Dysregulation of EED has been linked to various diseases including cancer, developmental disorders, and neurological conditions.
By targeting EED with this specific antibody, researchers can investigate its function and potential therapeutic targets in these disease contexts.With its high specificity and sensitivity, the EED Polyclonal Antibody (CAB12773) enables precise detection and analysis of EED protein levels in different cell types and tissues. By understanding the molecular mechanisms involving EED, researchers can gain insights into epigenetic regulation and gene expression, paving the way for novel therapeutic approaches in various fields of biomedical research.
Product Name:
EED Rabbit Polyclonal Antibody
SKU:
CAB12773
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EED (NP_003788.2).
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
8726
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EED Rabbit pAb (CAB12773) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
