The EDG1 Rabbit Monoclonal Antibody (CAB3997) is an essential tool for research involving the EDG1 protein, a key player in the regulation of various cellular functions, including cell growth, survival, and migration. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity towards the EDG1 protein in human samples, making it ideal for use in Western blot applications.The EDG1 protein, also known as sphingosine-1-phosphate receptor 1 (S1PR1), is involved in signaling pathways that control diverse physiological processes such as immune response modulation, vascular development, and cell trafficking.
Dysregulation of the EDG1 protein has been implicated in various diseases, including cancer, cardiovascular disorders, and immune-related conditions. By studying the function and expression of EDG1 using this monoclonal antibody, researchers can gain critical insights into its role in disease pathogenesis and potential therapeutic targets.Overall, the EDG1 Rabbit Monoclonal Antibody (CAB3997) holds great promise for advancing research in fields such as immunology, oncology, and cardiovascular biology, providing valuable tools for investigating the intricate mechanisms underlying cellular signaling and disease progression.
Product Name:
EDG1/HEXIM1 Rabbit Monoclonal Antibody
SKU:
CAB3997
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EDG1/HEXIM1 (P21453).
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1901
Clone Number:
ARC0881
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using EDG1/HEXIM1 Rabbit mAb (CAB3997) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
