EDEM2 Rabbit Polyclonal Antibody (CAB17181)
- SKU:
- CAB17181
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | EDEM2 Rabbit Polyclonal Antibody |
SKU: | CAB17181 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 399-578 of human EDEM2 (NP_060687.2). |
Sequence: | SIEK ISKV ECGF ATIK DLRD HKLD NRME SFFL AETV KYLY LLFD PTNF IHNN GSTF DAVI TPYG ECIL GAGG YIFN TEAH PIDP AALH CCQR LKEE QWEV EDLM REFY SLKR SRSK FQKN TVSS GPWE PPAR PGTL FSPE NHDQ ARER KPAK QKVP LLSC PSQP FTSK LALL GQVF LDSS |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | C20orf31; C20orf49; bA4204.1; EDEM2 |
Positive Sample: | A375,HepG2 |
Cellular Localization: | endoplasmic reticulum, endoplasmic reticulum lumen, endoplasmic reticulum quality control compartment |
Calculated MW: | 65kDa |
Observed MW: | 70kDa |
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).
Purification Method: | Affinity purification |
Gene ID: | 55741 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |