The EDC3 Polyclonal Antibody (CAB13763) is an essential tool for research involving EDC3, a key player in RNA metabolism and processing. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the EDC3 protein, this antibody allows for the detection and analysis of EDC3 in various cell types, making it a valuable resource for studies in RNA biology and gene expression regulation. EDC3 is a crucial component of RNA processing complexes, contributing to mRNA decay and quality control mechanisms in the cell. Dysregulation of EDC3 has been linked to various diseases, including cancer and neurodegenerative disorders, highlighting its importance in cellular homeostasis.
Investigating the functions of EDC3 using this antibody can provide valuable insights into RNA metabolism and its implications in disease development. Overall, the EDC3 Polyclonal Antibody is a reliable tool for researchers studying RNA biology and gene expression regulation, offering high specificity and sensitivity for the detection of EDC3 in human samples. Its utility extends to a wide range of applications, making it a valuable asset for research in molecular biology and disease mechanisms.
Product Name:
EDC3 Rabbit Polyclonal Antibody
SKU:
CAB13763
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 159-508 of human EDC3 (NP_079359.2).
This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability.
Purification Method:
Affinity purification
Gene ID:
80153
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using EDC3 Rabbit pAb (CAB13763) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
