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EDAR Monoclonal Antibody [PAT19E8AT] (CPAB0624)

SKU:
CPAB0624
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT19E8AT
Applications:
WB
ELISA
$179
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Description

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EDAR Monoclonal Antibody [PAT19E8AT] (CPAB0624)

The EDAR Polyclonal Antibody (CPAB0624) is a crucial tool for researchers studying EDAR, a member of the tumor necrosis factor (TNF) receptor superfamily. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. By targeting the EDAR protein, this antibody enables the detection and analysis of EDAR in various cell types, making it an excellent choice for investigations in immunology and cancer research.

EDAR plays a crucial role in the activation of the NF-kappa-B signaling pathway and is involved in processes such as cell survival, proliferation, and differentiation. Its significance in these pathways makes it a valuable target for research into various diseases, including cancer, inflammatory disorders, and immune-related conditions. Understanding the functions of EDAR is essential for the development of therapeutic strategies that can manipulate these pathways for clinical benefit.

Product Name:EDAR Antibody
Product Sku:CPAB0624
Size:5μg
Host Species:Mouse
Immunogen:Anti-human EDAR mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human EDAR protein 27-448 amino acids purified from Ecoli.
Clone:PAT19E8AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:EDAR antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:Ectodysplasin A Receptor, also known as EDAR belongs to the tumor necrosis factor receptor family. EDAR is a receptor for the soluble ligand ectodysplasin A, and is capable of activating the nuclear factor-kappaB, JNK, as well as caspase-independent cell death pathways. EDAR is necessary for the development of hair, teeth, and other ectodermal derivatives. Furthermore, mutations in EDAR resulted in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
Synonyms:Ectodysplasin A Receptor, DL, Ectodysplasin 1, Anhidrotic Receptor, Anhidrotic Ectodysplasin Receptor 1, Ectodermal Dysplasia Receptor, Ectodysplasin-A Receptor, Downless Homolog, EDA-A1 Receptor, ECTD10A, ECTD10B, EDA3, HRM1, ED3, Tumor Necrosis Factor Receptor Superfamily Member EDAR, Downless, Mouse, Homolog Of, EDA-A1R, EDA1R, ED1R, ED5, Tumor necrosis factor receptor superfamily member EDAR.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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