The ECM1 Polyclonal Antibody (CAB16368) is a valuable tool for research involving ECM1, a glycoprotein involved in cell adhesion and proliferation. The antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in various applications including Western blot and immunohistochemistry.ECM1, or extracellular matrix protein 1, is essential for maintaining the structural integrity of tissues and plays a crucial role in processes such as wound healing and tissue remodeling. Dysregulation of ECM1 has been implicated in various diseases including cancer and fibrotic disorders, making it a promising target for therapeutic interventions.
With its ability to specifically bind to ECM1, this polyclonal antibody enables researchers to detect and analyze the expression of ECM1 in different cell types and tissue samples. Its reliable performance and versatility make it an indispensable tool for studies in cell biology, cancer research, and tissue engineering. Understanding the function of ECM1 is key to developing treatments that target the extracellular matrix and its role in disease progression.
Product Name:
ECM1 Rabbit Polyclonal Antibody
SKU:
CAB16368
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 280-405 of human ECM1 (NP_004416.2).
This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
1893
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ECM1 Rabbit pAb (CAB16368) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
