The ECI2 Polyclonal Antibody (CAB13072) is a vital tool for researchers studying ECI2, a protein involved in various cellular processes including antioxidant defense and lipid metabolism. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it an ideal choice for immunohistochemistry and immunofluorescence applications. By binding to the ECI2 protein, researchers can visualize and analyze its expression in different cell types, enabling a deeper understanding of its role in cellular function and disease processes.
Known for its involvement in maintaining cellular homeostasis and protecting against oxidative stress, ECI2 has been implicated in a range of pathologies, including metabolic disorders and neurodegenerative diseases. Investigating the function of ECI2 using this polyclonal antibody can provide valuable insights into potential therapeutic targets for conditions related to cellular dysfunction and oxidative damage. Researchers aiming to unravel the complexities of ECI2 biology will find this antibody indispensable for their experiments.
Product Name:
ECI2 Rabbit Polyclonal Antibody
SKU:
CAB13072
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human ECI2 (NP_006108.2).
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
10455
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ECI2 Rabbit pAb (CAB13072) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.