The ECI1 Polyclonal Antibody (CAB1211) is a valuable tool for researchers studying ECI1, a protein involved in lipid metabolism and cell signaling pathways. This antibody, produced in rabbits, is highly specific for detecting ECI1 in human samples and is validated for use in Western blot applications. By binding to the ECI1 protein, this antibody allows for precise detection and analysis of ECI1 expression in various cell types, making it an essential tool for studies in lipid metabolism, cell signaling, and related fields.
ECI1, also known as enoyl-CoA delta isomerase 1, is a key enzyme in fatty acid oxidation and plays a crucial role in maintaining lipid homeostasis within cells. Dysregulation of ECI1 has been implicated in various metabolic disorders, making it a potential therapeutic target for conditions such as obesity, diabetes, and cardiovascular disease. Research into the function and regulation of ECI1 is essential for developing targeted therapies aimed at modulating lipid metabolism and treating associated diseases.
Product Name:
ECI1 Rabbit Polyclonal Antibody
SKU:
CAB1211
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 63-302 of human ECI1 (NP_001910.2).
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
1632
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using ECI1 Rabbit pAb (CAB1211) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 45s.
