ECH1 Rabbit Polyclonal Antibody (CAB12944)
- SKU:
- CAB12944
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | ECH1 Rabbit Polyclonal Antibody |
SKU: | CAB12944 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-328 of human ECH1 (NP_001389.2). |
Sequence: | MAAG IVAS RRLR DLLT RRLT GSNY PGLS ISLR LTGS SAQE EASG VALG EAPD HSYE SLRV TSAQ KHVL HVQL NRPN KRNA MNKV FWRE MVEC FNKI SRDA DCRA VVIS GAGK MFTA GIDL MDMA SDIL QPKG DDVA RISW YLRD IITR YQET FNVI ERCP KPVI AAVH GGCI GGGV DLVT ACDI RYCA QDAF FQVK EVDV GLAA DVGT LQRL PKVI GNQS LVNE LAFT ARKM MADE ALGS GLVS RVFP DKEV MLDA ALAL AAEI SSKS PVAV QSTK VNLL YSRD HSVA ESLN YVAS WNMS MLQT QDLV KSVQ ATTE NKEL KTVT FSKL |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HPXEL; ECH1 |
Positive Sample: | Hep G2,Rat heart,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion, Peroxisome. |
Calculated MW: | 36kDa |
Observed MW: | 36kDa |
This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.
Purification Method: | Affinity purification |
Gene ID: | 1891 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |