The E2F8 Polyclonal Antibody (CAB1135) is a valuable tool for researchers studying E2F8, a transcription factor known for its role in cell cycle regulation and tumorigenesis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the E2F8 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in cancer biology and cell signaling pathways.
E2F8 is a key player in controlling cell growth and proliferation, making it a promising target for therapeutic interventions in cancer treatment. Understanding the molecular mechanisms underlying E2F8 function is essential for developing targeted therapies that can effectively block tumor progression. The E2F8 Polyclonal Antibody provides researchers with a reliable tool to further explore the role of E2F8 in cancer biology and potentially identify new strategies for cancer therapy.
Product Name:
E2F8 Rabbit Polyclonal Antibody
SKU:
CAB1135
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 788-867 of human E2F8 (NP_078956.2).
This gene encodes a member of a family of transcription factors which regulate the expression of genes required for progression through the cell cycle. The encoded protein regulates progression from G1 to S phase by ensuring the nucleus divides at the proper time. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method:
Affinity purification
Gene ID:
79733
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using E2F8 Rabbit pAb (CAB1135) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).
