E2F6 Polyclonal Antibody (CAB6151)
- SKU:
- CAB6151
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- IF
- IP
- ChIP
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | E2F6 Polyclonal Antibody |
SKU: | CAB6151 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human E2F6 (NP_937987.2). |
Sequence: | MSQQ RPAR KLPS LLLD PTEE TVRR RCRD PINV EGLL PSKI RINL EDNV QYVS MRKA LKVK RPRF DVSL VYLT RKFM DLVR SAPG GILD LNKV ATKL GVRK RRVY DITN VLDG IDLV EKKS KNHI RWIG SDLS NFGA VPQQ KKLQ EELS DLSA MEDA LDEL IKDC AQQL FELT DDKE NERL AYVT YQDI HSIQ AFHE QIVI AVKA PAET RLDV PAPR EDSI TVHI RSTN GPID VYLC EVEQ GQTS NKRS EGVG TSSS ESTH PEGP EEEE NPQQ SEEL LEVS N |
Tested Applications: | WB IP ChIP ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cellsChIP,5μg antibody for 10μg-15μg of Chromatin |
Synonyms: | E2F-6; E2F6 |
Positive Sample: | HeLa,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 32kDa |
Observed MW: | 36kDa |
This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 1876 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |