SELE Rabbit Polyclonal Antibody (CAB2191)
- SKU:
- CAB2191
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SELE Rabbit Polyclonal Antibody |
SKU: | CAB2191 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-230 of human SELE (NP_000441.2). |
Sequence: | WSYN TSTE AMTY DEAS AYCQ QRYT HLVA IQNK EEIE YLNS ILSY SPSY YWIG IRKV NNVW VWVG TQKP LTEE AKNW APGE PNNR QKDE DCVE IYIK REKD VGMW NDER CSKK KLAL CYTA ACTN TSCS GHGE CVET INNY TCKC DPGF SGLK CEQI VNCT ALES PEHG SLVC SHPL GNFS YNSS CSIS CDRG YLPS SMET MQCM SSGE W |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ELAM; ESEL; CD62E; ELAM1; LECAM2; selectin-e; SELE |
Positive Sample: | SK-BR-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 67kDa |
Observed MW: | 67kDa |
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Purification Method: | Affinity purification |
Gene ID: | 6401 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |