Dystrophin Rabbit Polyclonal Antibody (CAB1411)
- SKU:
- CAB1411
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Dystrophin Rabbit Polyclonal Antibody |
SKU: | CAB1411 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 346-635 of human Dystrophin (NP_003997.2). |
Sequence: | TALE EVLS WLLS AEDT LQAQ GEIS NDVE VVKD QFHT HEGY MMDL TAHQ GRVG NILQ LGSK LIGT GKLS EDEE TEVQ EQMN LLNS RWEC LRVA SMEK QSNL HRVL MDLQ NQKL KELN DWLT KTEE RTRK MEEE PLGP DLED LKRQ VQQH KVLQ EDLE QEQV RVNS LTHM VVVV DESS GDHA TAAL EEQL KVLG DRWA NICR WTED RWVL LQDI LLKW QRLT EEQC LFSA WLSE KEDA VNKI HTTG FKDQ NEML SSLQ KLAV LKAD LEKK KQSM GKLY SLKQ DLLS TLKN KS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | BMD; CMD3B; MRX85; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; Dystrophin |
Positive Sample: | Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cytoskeleton, postsynaptic cell membrane, sarcolemma, synapse. |
Calculated MW: | 427kDa |
Observed MW: | 427kDa |
This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1756 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |