DAG1 Rabbit Polyclonal Antibody (CAB10076)
- SKU:
- CAB10076
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | DAG1 Rabbit Polyclonal Antibody |
SKU: | CAB10076 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 776-895 of human DAG1 (NP_001171108.1). |
Sequence: | RKKR KGKL TLED QATF IKKG VPII FADE LDDS KPPP SSSM PLIL QEEK APLP PPEY PNQS VPET TPLN QDTM GEYT PLRD EDPN APPY QPPP PFTA PMEG KGSR PKNM TPYR SPPP YVPP |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IF/ICC,1:20 - 1:100 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | A3a; DAG; AGRNR; 156DAG; MDDGA9; MDDGC7; MDDGC9; LGMDR16; DAG1 |
Positive Sample: | Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, Nucleus, Secreted, Single-pass type I membrane protein, cytoskeleton, extracellular space, nucleoplasm, postsynaptic cell membrane, sarcolemma, synapse. |
Calculated MW: | 97kDa |
Observed MW: | 43kDa |
This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.
Purification Method: | Affinity purification |
Gene ID: | 1605 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |