DTNA Rabbit Polyclonal Antibody (CAB12067)
- SKU:
- CAB12067
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DTNA Rabbit Polyclonal Antibody |
SKU: | CAB12067 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 240-480 of human DTNA (NP_001381.2). |
Sequence: | PVEC SYCH SESM MGFR YRCQ QCHN YQLC QDCF WRGH AGGS HSNQ HQMK EYTS WKSP AKKL TNAL SKSL SCAS SREP LHPM FPDQ PEKP LNLA HIVD TWPP RPVT SMND TLFS HSVP SSGS PFIT RSSP PKDS EVEQ NKLL ARAA PAFL KGKG IQYS LNVA DRLA DEHV LIGL YVNM LRNN PSCM LESS NRLD EEHR LIAR YAAR LAAE SSSS QPPQ QRSA PDIS FTID ANKQ QRQL IAEL E |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | DTN; DRP3; DTN-A; LVNC1; D18S892E; DTNA |
Positive Sample: | U-87MG,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell membrane, Cytoplasm, synapse. |
Calculated MW: | 84kDa |
Observed MW: | 84kDa |
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1837 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |