The Dysbindin Polyclonal Antibody (CAB1632) is a valuable tool for researchers studying dysbindin, a protein involved in neural development and synaptic function. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in various applications, including Western blot analysis.Dysbindin is known to be associated with schizophrenia and other neurodevelopmental disorders, making it an important target for research in the field of neuroscience. By enabling the detection and analysis of dysbindin in different cell types, this antibody is ideal for studies aiming to unravel the role of dysbindin in the pathophysiology of these disorders.
The Dysbindin Polyclonal Antibody holds great potential for advancing our understanding of dysbindin's function and its implications in neurological diseases. Researchers in the fields of neuroscience, psychiatry, and pharmacology can benefit from using this antibody to explore new therapeutic targets and develop innovative treatments for debilitating conditions like schizophrenia.
Product Name:
DTNBP1 Rabbit Polyclonal Antibody
SKU:
CAB1632
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human DTNBP1 (NP_115498.2).
This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this gene are associated with Hermansky-Pudlak syndrome type 7. This gene may also be associated with schizophrenia. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Purification Method:
Affinity purification
Gene ID:
84062
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DTNBP1 antibody (CAB1632) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
