The DYRK4 Polyclonal Antibody (CAB16460) is a valuable tool for researchers studying the DYRK4 protein, which is involved in cell cycle regulation and development. Raised in rabbits, this antibody is highly specific to DYRK4 in human samples and is suitable for use in Western blot applications. By binding to DYRK4, researchers can detect and analyze the protein in various cell types, making this antibody ideal for studies in cell biology and developmental biology.DYRK4, a member of the dual-specificity tyrosine-phosphorylation-regulated kinase (DYRK) family, plays a crucial role in cell proliferation and differentiation.
Dysregulation of DYRK4 has been linked to various diseases, including cancer and neurodevelopmental disorders, making it an important target for research. By understanding the function of DYRK4, researchers can potentially develop targeted therapies for these conditions.Overall, the DYRK4 Polyclonal Antibody (CAB16460) provides researchers with a reliable tool for investigating the role of DYRK4 in cellular processes and disease development. Its high specificity and sensitivity make it a valuable asset for advancing our understanding of DYRK4 and its potential implications in human health.
Product Name:
DYRK4 Rabbit Polyclonal Antibody
SKU:
CAB16460
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human DYRK4 (NP_003836.1).
This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Purification Method:
Affinity purification
Gene ID:
8798
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DYRK4 Rabbit pAb (CAB16460) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
