The DynLT3 Polyclonal Antibody (CAB16982) is a valuable tool for researchers studying the dynactin complex, a critical component of intracellular transport pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to DynLT3, this antibody enables precise detection and analysis of this protein in a variety of cell types, making it an ideal choice for investigations in cell biology and neurology.DynLT3 is an essential subunit of the dynactin complex, which plays a key role in facilitating the movement of cellular cargoes along microtubules.
Dysfunction of this complex has been linked to various neurodegenerative disorders, making DynLT3 a promising target for research into conditions such as Alzheimer's and Parkinson's disease. By better understanding the function of DynLT3, researchers can uncover new insights into the mechanisms underlying these diseases and potentially identify novel therapeutic approaches.
Product Name:
DYNLT3 Rabbit Polyclonal Antibody
SKU:
CAB16982
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 9-99 of human DYNLT3 (NP_006511.1).
This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.
Purification Method:
Affinity purification
Gene ID:
6990
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DYNLT3 Rabbit pAb (CAB16982) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
