The DynLRB1 Polyclonal Antibody (CAB15197) is a valuable tool for researchers studying DynLRB1, a protein involved in cellular processes such as proliferation, differentiation, and apoptosis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is verified for use in Western blot applications. By binding to DynLRB1, the antibody enables accurate detection and analysis in various cell types, making it an excellent choice for investigations in cell biology and cancer research.
DynLRB1, also known as a dynamic LPS-responsive Beige-like anchor protein 1, plays a crucial role in cell signaling pathways that regulate cell growth and survival. Its involvement in these processes makes it a key target for research on diseases like cancer and neurodegenerative disorders. By understanding the function of DynLRB1, researchers can explore potential therapeutic strategies that target this protein to manipulate cellular behavior in pathological conditions.
Product Name:
DYNLRB1 Rabbit Polyclonal Antibody
SKU:
CAB15197
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-63 of human DYNLRB1 (NP_001268656.1).
This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18.
Purification Method:
Affinity purification
Gene ID:
83658
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using DYNLRB1 Rabbit pAb (CAB15197) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
