The DYNLL2 Polyclonal Antibody (CAB13888) is a valuable tool for researchers studying the DYNLL2 protein, which is involved in various cellular processes, including intracellular transport and cell division. This antibody, produced through immunization of rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to DYNLL2, it enables accurate detection and analysis of the protein in diverse cell types, making it ideal for investigations in cell biology and cancer research.DYNLL2, also known as dynein light chain LC8-type 2, plays a crucial role in the function of molecular motor proteins and the regulation of intracellular trafficking.
Its involvement in processes essential for cell division and movement highlights its importance in both normal cellular function and disease states. Research on DYNLL2 can provide insights into mechanisms underlying cancer progression, neurodegenerative disorders, and other conditions related to cellular dysfunction. Just as with CD300A, understanding the function of DYNLL2 can drive the development of novel therapeutic strategies targeted at these diseases.
Product Name:
DYNLL2 Rabbit Polyclonal Antibody
SKU:
CAB13888
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-89 of human DYNLL2 (NP_542408.1).
Predicted to enable dynein intermediate chain binding activity and dynein light intermediate chain binding activity. Predicted to be involved in cilium assembly. Located in 9+0 non-motile cilium and centrosome. Is active in glutamatergic synapse and postsynapse.
Purification Method:
Affinity purification
Gene ID:
140735
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DYNLL2 Rabbit pAb (CAB13888) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
