DYNLL1 Rabbit Monoclonal Antibody (CAB4353)
- SKU:
- CAB4353
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Description
Product Name: | DYNLL1 Rabbit Monoclonal Antibody |
SKU: | CAB4353 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-89 of human DYNLL1 (P63167). |
Sequence: | MCDR KAVI KNAD MSEE MQQD SVEC ATQA LEKY NIEK DIAA HIKK EFDK KYNP TWHC IVGR NFGS YVTH ETKH FIYF YLGQ VAIL LFKS G |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | LC8; PIN; DLC1; DLC8; LC8a; DNCL1; hdlc1; DNCLC1; DYNLL1 |
Positive Sample: | HeLa,U-87MG,Mouse testis,Mouse brain,Rat lung,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion, Nucleus, cytoskeleton. |
Calculated MW: | 10kDa |
Observed MW: | 10kDa |
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 8655 |
Clone Number: | ARC0975 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |