The DYNLL1 Rabbit Monoclonal Antibody (CAB4353) is a cutting-edge research tool designed for the study of DYNLL1, a crucial protein involved in cellular processes such as intracellular transport and cell division. This antibody, generated in rabbits, demonstrates high specificity and sensitivity towards human samples, making it an ideal choice for a variety of research applications.With its optimized performance in Western blot experiments, the DYNLL1 Rabbit Monoclonal Antibody enables precise detection and analysis of the DYNLL1 protein across different cell types and experimental conditions. This makes it an invaluable tool for researchers working in the fields of cell biology, molecular biology, and cancer research.DYNLL1, also known as dynein light chain LC8-type 1, plays a vital role in intracellular transport processes by binding to cytoplasmic dynein and facilitating the movement of cargo along microtubules.
Dysregulation of DYNLL1 has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting the importance of studying this protein for potential therapeutic interventions.By utilizing the DYNLL1 Rabbit Monoclonal Antibody in your research, you can gain valuable insights into the functions and regulatory mechanisms of DYNLL1, ultimately contributing to a better understanding of cellular processes and disease mechanisms. Whether investigating basic biological functions or exploring potential therapeutic targets, this antibody is a powerful tool for advancing scientific knowledge and discovery.
Product Name:
DYNLL1 Rabbit Monoclonal Antibody
SKU:
CAB4353
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-89 of human DYNLL1 (P63167).
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
Purification Method:
Affinity purification
Gene ID:
8655
Clone Number:
ARC0975
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using DYNLL1 Rabbit mAb (CAB4353) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
