DYNLL1 Monoclonal Antibody [PAT13C9AT] (CPAB0645)
- SKU:
- CPAB0645
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT13C9AT
- Applications:
- WB
- ELISA
Description
DYNLL1 Monoclonal Antibody [PAT13C9AT] (CPAB0645)
The DYNLL1 Monoclonal Antibody (CPAB0645) is a valuable tool for researchers studying the DYNLL1 protein, a key component of the dynein complex involved in intracellular transport and cell division. This antibody, derived from mouse hybridoma cells, is highly specific and reacts with human samples, making it ideal for a variety of applications including Western blot and immunofluorescence.DYNLL1, also known as dynein light chain LC8-type 1, is essential for dynein function and plays a crucial role in various cellular processes such as organelle transport, mitosis, and cell migration.
Dysregulation of DYNLL1 has been linked to diseases like cancer and neurodegenerative disorders, highlighting its importance in pathological conditions. By targeting DYNLL1 with this antibody, researchers can study its expression, localization, and interactions in different cell types, providing valuable insights into its role in health and disease.
Product Name: | DYNLL1 Antibody |
Product Sku: | CPAB0645 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human DYNLL1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human DYNLL1 protein 1-89 amino acids purified from Ecoli. |
Clone: | PAT13C9AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | DYNLL1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1 |
Background: | DYNLL1 is a protein that cooperates with NOS1 causing NOS1 inhibition. Binding of DYNLL1 weakens NOS1 (Neuronal nitric oxide synthase) dimer, a conformation needed for activity, and it regulates several biologic processes through its effects on nitric oxide synthase activity. DYNLL1 is a ubiquitously expressed protein that demonstrates high expression in testis and moderate expression in brain. |
Synonyms: | PIN, DLC1, DLC8, DNCL1, DNCLC1, Dynein Light Chain LC8-type 1, Dynein Cytoplasmic Light polypeptide 1, Protein Inhibitor of Neuronal Nitric Oxide Synthase, DYNLL1. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |