DYNC2LI1 Rabbit Polyclonal Antibody (CAB4752)
- SKU:
- CAB4752
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DYNC2LI1
- CGI-60
- D2LIC
- LIC3
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DYNC2LI1 Rabbit Polyclonal Antibody |
SKU: | CAB4752 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-352 of human DYNC2LI1 (NP_001180393.1). |
Sequence: | MPSE TLWE IAKA EVEK RGIN GSEG DGAE IAEK FVFF IGSK NGGK TTII LRCL DRDE PPKP TLAL EYTY GRRA KGHN TPKD IAHF WELG GGTS LLDL ISIP ITGD TLRT FSLV LVLD LSKP NDLW PTME NLLQ ATKS HVDK VIMK LGKT NAKA VSEM RQKI WNNM PKDH PQDH ELID PFPV PLVI IGSK YDVF QDFE SEKR KVIC KTLR FVAH YYGA SLMF TSKS EALL LKIR GVIN QLAF GIDK SKSI CVDQ NKPL FITA GLDS FGQI GSPP VPEN DIGK LHAH SPME LWKK VYEK LFPP KSIN TLKD IKDP ARDP QYAE NEVD EMRI QKDL ELEQ YKRS SSKS WKQI ELDS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LIC3; D2LIC; CGI-60; DYNC2LI1 |
Positive Sample: | U-251MG,Jurkat,293T,A-549,Mouse testis,Mouse eye,Mouse kidney,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, cilium axoneme, cytoskeleton. |
Calculated MW: | 40kDa |
Observed MW: | 38kDa |
This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 51626 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |