The DYNC1I1 Polyclonal Antibody (CAB3833) is a valuable tool for researchers studying the DYNC1I1 protein, which is involved in cellular transport processes within the cell. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the DYNC1I1 protein, this antibody allows for the detection and analysis of DYNC1I1 in various cell types, making it an ideal choice for studies in cell biology and neurology.DYNC1I1 is a key component of the dynein complex, which plays a crucial role in intracellular transport along microtubules.
Dysregulation of this process has been linked to neurodegenerative disorders such as Alzheimer's disease and Huntington's disease. Therefore, researchers investigating the function and regulation of DYNC1I1 have the potential to uncover new insights into these debilitating conditions.Overall, the DYNC1I1 Polyclonal Antibody (CAB3833) offers researchers a reliable tool for studying the role of DYNC1I1 in cellular transport processes and its implications for neurodegenerative diseases. Its high specificity and sensitivity make it a valuable asset in furthering our understanding of these important biological mechanisms.
Product Name:
DYNC1I1 Rabbit Polyclonal Antibody
SKU:
CAB3833
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DYNC1I1 (NP_001129028.1).
Chromosome, Cytoplasm, centromere, cytoskeleton, kinetochore, spindle pole.
Calculated MW:
73kDa
Observed MW:
73kDa
Enables spectrin binding activity. Involved in vesicle transport along microtubule. Located in several cellular components, including kinetochore; recycling endosome; and spindle pole.
Purification Method:
Affinity purification
Gene ID:
1780
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DYNC1I1 Rabbit pAb (CAB3833) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
