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DYNC1H1 Polyclonal Antibody (CAB18314)

SKU:
CAB18314
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
$155 - $431
Frequently bought together:

Description

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DYNC1H1 Polyclonal Antibody (CAB18314)

The Dynactin 1 (DCTN1) Polyclonal Antibody (CAB18314) is crafted for investigations involving DCTN1, a key protein involved in intracellular transport and cytoskeletal organization. This antibody, produced in rabbits, exhibits high reactivity towards human samples and has been rigorously validated for use in Western blotting applications. By specifically binding to the DCTN1 protein, this antibody enables accurate detection and analysis across various cell types, making it an invaluable tool for studies in cell biology and neurodegenerative diseases.

DCTN1, also known as p150 Glued, plays a crucial role in linking vesicles to cytoplasmic dynein during retrograde transport along microtubules. Dysfunction or dysregulation of DCTN1 has been implicated in neurodegenerative disorders like amyotrophic lateral sclerosis (ALS) and Charcot-Marie-Tooth disease (CMT). Understanding the function and regulation of DCTN1 is essential for unraveling the pathophysiology of these conditions and may offer insights into potential therapeutic targets for treating these debilitating diseases.