DNM2 Rabbit Polyclonal Antibody (CAB0523)
- SKU:
- CAB0523
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | DNM2 Rabbit Polyclonal Antibody |
SKU: | CAB0523 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 607-866 of human DNM2 (NP_004936.2). |
Sequence: | EDVD SWKA SFLR AGVY PEKD QAEN EDGA QENT FSMD PQLE RQVE TIRN LVDS YVAI INKS IRDL MPKT IMHL MINN TKAF IHHE LLAY LYSS ADQS SLME ESAD QAQR RDDM LRMY HALK EALN IIGD ISTS TVST PVPP PVDD TWLQ SASS HSPT PQRR PVSS IHPP GRPP AVRG PTPG PPLI PVPV GAAA SFSA PPIP SRPG PQSV FANS DLFP APPQ IPSR PVRI PPGI PPGV PSRR PPAA PSRP TIIR PAEP SLLD |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | DYN2; CMT2M; DYNII; LCCS5; CMTDI1; CMTDIB; DI-CMTB; DNM2 |
Positive Sample: | BT-474,MCF7,SKOV3,Mouse testis,Mouse heart,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cytoplasm, Membrane, Midbody, clathrin-coated pit, cytoskeleton, postsynaptic cell membrane, postsynaptic density, synapse. |
Calculated MW: | 98kDa |
Observed MW: | 110kDa |
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 1785 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |