The Dvl2 Polyclonal Antibody (CAB7551) is a valuable tool for researchers studying the Dishevelled 2 (Dvl2) protein, a key player in the Wnt signaling pathway. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the Dvl2 protein, this antibody enables researchers to detect and analyze the expression levels and activity of Dvl2 in various cell types. This makes it ideal for studies in developmental biology, cancer research, and other fields where the Wnt signaling pathway is a key focus. The Wnt signaling pathway is crucial for the regulation of cell proliferation, differentiation, and migration, making the Dvl2 protein an important target for research.
By understanding the role of Dvl2 in this pathway, researchers can gain insights into the mechanisms underlying development, cancer progression, and other biological processes. Overall, the Dvl2 Polyclonal Antibody (CAB7551) is a valuable tool for researchers looking to investigate the function of the Dvl2 protein and its role in cellular signaling pathways. Its specificity and reliability make it a trusted resource for studies aiming to uncover the complexities of Wnt signaling and its implications in various physiological and pathological conditions.
Product Name:
DVL2 Rabbit Polyclonal Antibody
SKU:
CAB7551
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 600-700 of human DVL2 (NP_004413.1).
This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
Purification Method:
Affinity purification
Gene ID:
1856
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of NIH/3T3 cells using DVL2 antibody (CAB7551) at dilution of 1:100. Blue: DAPI for nuclear staining.
