DVL1 Rabbit Polyclonal Antibody (CAB10536)
- SKU:
- CAB10536
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | DVL1 Rabbit Polyclonal Antibody |
SKU: | CAB10536 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 510-640 of human DVL1 (NP_004412.2). |
Sequence: | GQGY PYQY PGPP PCFP PAYQ DPGF SYGS GSTG SQQS EGSK SSGS TRSS RRAP GREK ERRA AGAG GSGS ESDH TAPS GVGS SWRE RPAG QLSR GSSP RSQA SATA PGLP PPHP TTKA YTVV GGPP GGPP VRE |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | DVL; DRS2; DVL1L1; DVL1P1; DVL1 |
Positive Sample: | HeLa,PC-3,293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Peripheral membrane protein, cytosol. |
Calculated MW: | 75kDa |
Observed MW: | 75kDa |
DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.
Purification Method: | Affinity purification |
Gene ID: | 1855 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |