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DUSP3 Monoclonal Antibody [PAT9E6AT] (CPAB0208)

SKU:
CPAB0208
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT9E6AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

DUSP3 Monoclonal Antibody [PAT9E6AT] (CPAB0208)

The DUSP3 Polyclonal Antibody (CPAB0208) is a reliable tool for investigating the function of DUSP3, a dual-specificity phosphatase involved in the regulation of various signaling pathways. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in Western blot applications.DUSP3 plays a key role in the dephosphorylation of MAP kinases, contributing to the regulation of cell growth, differentiation, and apoptosis. Its dysregulation has been implicated in various diseases, including cancer, inflammatory disorders, and neurodegenerative conditions.

The DUSP3 Polyclonal Antibody enables the detection and analysis of DUSP3 protein levels in different cell types, making it a valuable tool for research in molecular biology, oncology, and drug development.Elucidating the function of DUSP3 is essential for understanding its role in disease pathogenesis and identifying potential therapeutic targets. By studying the activity of DUSP3, researchers can uncover new insights into cell signaling mechanisms and potentially develop novel treatments for a range of health conditions.

Product Name:DUSP3 Antibody
Product Sku:CPAB0208
Size:5μg
Host Species:Mouse
Immunogen:Anti-human DUSP3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human DUSP3 amino acids 1-185 purified from Ecoli.
Clone:PAT9E6AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:DUSP3 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:DUSP3 belongs to the dual specificity protein phosphatase subfamily which inactivates their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSP3 negatively regulate members of the mitogen-activated protein kinase superfamily that are related to cellular proliferation and differentiation. DUSP3 is expressed in both breast and ovarian tissues and displays activity both for tyrosine-protein phosphate and serine-protein phosphate, but exhibits a strong preference toward phosphotyrosines, specifically dephosphorylates and inactivates ERK1 and ERK2.
Synonyms:Dual specificity phosphatase 3, VHR, Vaccinia virus phosphatase VH1-related, Dual specificity protein phosphatase VHR, Vaccinia H1-related phosphatase, serine/threonine specific protein phosphatase, DUSP3.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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