The DUSP23 Antibody (PAC016208) is a vital tool for researchers studying the dual-specificity phosphatase 23 (DUSP23) protein, which plays a key role in the regulation of cellular processes such as growth and differentiation. This polyclonal antibody, produced in rabbits, exhibits high reactivity towards human samples and has been validated for use in Western blot applications.DUSP23 is known for its involvement in signaling pathways that govern cell proliferation and survival, making it a promising target for investigations into cancer biology and developmental biology. By specifically binding to the DUSP23 protein, this antibody allows for the accurate detection and analysis of DUSP23 expression in various cell types, providing valuable insight into its function and potential therapeutic applications.
In summary, the DUSP23 Antibody (PAC016208) is a valuable tool for researchers seeking to explore the role of DUSP23 in cellular mechanisms and disease pathways. Its specificity and reliability make it an essential component of studies focusing on cancer research, developmental biology, and therapeutic interventions targeting aberrant cell signaling.
Antibody Name:
DUSP23 Antibody (PACO16208)
Antibody SKU:
PACO16208
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse
Immunogen:
Fusion protein of human DUSP23
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16208(DUSP23 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO16208(DUSP23 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200).
Background:
Dual specificity protein phosphatase 23, also known as low molecular mass dual specificity phosphatase 3 (LDP-3), is an enzyme that in humans is encoded by the DUSP23 gene.
Synonyms:
dual specificity phosphatase 23
UniProt Protein Function:
Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14).
