The DUSP16 Polyclonal Antibody (CAB10155) is a valuable tool for research involving DUSP16, a dual-specificity phosphatase that plays a role in regulating cell growth, differentiation, and apoptosis. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding to the DUSP16 protein, it allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in cell signaling pathways and cancer research.
DUSP16, also known as MKP-7, is a key player in controlling MAPK signaling cascades and has been implicated in various cellular processes, including stress responses and cell cycle regulation. Its dysregulation has been linked to cancer progression and other diseases, making it a promising target for therapeutic interventions. Understanding the function of DUSP16 is essential for developing targeted treatments that can modulate cell signaling and inhibit tumor growth in cancer patients.
Product Name:
DUSP16 Rabbit Polyclonal Antibody
SKU:
CAB10155
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 416-665 of human DUSP16 (NP_085143.1).
This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. The encoded protein specifically regulates the c-Jun amino-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) pathways.
Purification Method:
Affinity purification
Gene ID:
80824
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DUSP16 antibody (CAB10155) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
