DUSP10 Rabbit Polyclonal Antibody (CAB8748)
- SKU:
- CAB8748
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | DUSP10 Rabbit Polyclonal Antibody |
SKU: | CAB8748 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human DUSP10 (NP_009138.1). |
Sequence: | MPPS PLDD RVVV ALSR PVRP QDLN LCLD SSYL GSAN PGSN SHPP VIAT TVVS LKAA NLTY MPSS SGSA RSLN CGCS SASC CTVA TYDK DNQA QTQA IAAG TTTT AIGT STTC PANQ MVNN NENT GSLS PSSG VGSP VSGT PKQL ASIK IIYP NDLA KKMT KCSK SHLP SQGP VIID CRPF MEYN KSHI QGAV HINC ADKI SRRR LQQG KITV LDLI SCRE GKDS FKRI FSKE IIVY DENT NEPS RVMP SQPL HIVL ESLK REGK EPLV LKGG LSSF KQNH ENLC DNSL QLQE CREV GGGA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MKP5; MKP-5; DUSP10 |
Positive Sample: | BT-474 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 53kDa |
Observed MW: | 53kDa |
Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 11221 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |