DUSP1/MKP1 Rabbit Polyclonal Antibody (CAB2919)
- SKU:
- CAB2919
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | DUSP1/MKP1 Rabbit Polyclonal Antibody |
SKU: | CAB2919 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human DUSP1/MKP1 (NP_004408.1). |
Sequence: | MVME VGTL DAGG LRAL LGER AAQC LLLD CRSF FAFN AGHI AGSV NVRF STIV RRRA KGAM GLEH IVPN AELR GRLL AGAY HAVV LLDE RSAA LDGA KRDG TLAL AAGA LCRE ARAA QVFF LKGG YEAF SASC PELC SKQS TPMG LSLP LSTS VPDS AESG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | HVH1; MKP1; CL100; MKP-1; PTPN10; DUSP1/MKP1 |
Positive Sample: | Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 39kDa |
Observed MW: | 40kDa |
The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.
Purification Method: | Affinity purification |
Gene ID: | 1843 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |