DUSP1/MKP1 Monoclonal Antibody (CAB22201)
- SKU:
- CAB22201
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | DUSP1/MKP1 Monoclonal Antibody |
SKU: | CAB22201 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DUSP1/MKP1 (NP_004408.1). |
Sequence: | GTLA LAAG ALCR EARA AQVF FLKG GYEA FSAS CPEL CSKQ STPM GLSL PLST SVPD SAES GCSS CSTP LYDQ GGPV EILP FLYL GSAY HASR KDML DALG I |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | HVH1; MKP1; CL100; MKP-1; PTPN10; DUSP1/MKP1 |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 39kDa |
Observed MW: | 39kDa |
The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy.
Purification Method: | Affinity purification |
Gene ID: | 1843 |
Clone Number: | ARC56245 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |