The DUS3L Polyclonal Antibody (PACO38982) is a valuable tool for researchers studying DUS3L, a protein involved in RNA processing and stability. This antibody, produced in rabbits, boasts high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the DUS3L protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and genetics.DUS3L is known for its role in RNA modification and processing, playing a crucial part in maintaining genomic stability and regulating gene expression.
Its involvement in these essential cellular processes makes it a promising target for studies related to genetic diseases, cancer, and developmental disorders. By delving into the functions of DUS3L, researchers can gain valuable insights into the mechanisms governing RNA metabolism and potentially uncover new therapeutic targets for various conditions.
Antibody Name:
DUS3L Antibody (PACO38982)
Antibody SKU:
PACO38982
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human tRNA-dihydrouridine (47) synthase [NAD(P) protein (221-409AA)
DUS3L: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Belongs to the dus family. Dus3 subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 1.-.-.-; EC 1.3.1.-; OxidoreductaseChromosomal Location of Human Ortholog: 19p13.3Cellular Component: cytosolMolecular Function: FAD binding; metal ion binding; tRNA dihydrouridine synthase activity