The DTX2 Polyclonal Antibody (CAB7398) is a valuable tool for researchers studying the DTX2 protein, a key player in the Notch signaling pathway. This antibody, produced in rabbits, exhibits high specificity for human samples and is optimized for use in Western blot applications. By targeting the DTX2 protein, researchers can investigate its role in cell signaling and its potential as a therapeutic target in diseases like cancer and developmental disorders.
DTX2 is a critical regulator of Notch signaling, which plays a crucial role in cell differentiation, proliferation, and survival. Dysregulation of the Notch pathway has been implicated in various diseases, making DTX2 an attractive target for further study. The DTX2 Polyclonal Antibody enables researchers to detect and analyze DTX2 expression in a variety of cell types, providing insight into its function and potential as a therapeutic target.
Product Name:
DTX2 Rabbit Polyclonal Antibody
SKU:
CAB7398
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human DTX2 (NP_065943.2).
DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 [PubMed 12670957]).
Purification Method:
Affinity purification
Gene ID:
113878
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using DTX2 Rabbit pAb (CAB7398) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
