The DSP Polyclonal Antibody (CAB13299) is a valuable tool for researchers studying DSP, a critical protein involved in cell-cell adhesion and communication in tissues like the heart and skin. This antibody, produced in rabbits, shows high specificity and sensitivity towards DSP in human samples, making it ideal for use in Western blot applications.DSP, also known as desmoplakin, is essential for maintaining the structural integrity of tissues by forming connections between cells. Dysregulation of DSP has been linked to various diseases, including cardiomyopathies and skin disorders.
By using the DSP Polyclonal Antibody, researchers can investigate the expression and localization of DSP in different cell types and tissues, advancing our understanding of its role in health and disease.Overall, the DSP Polyclonal Antibody is a reliable tool for studying DSP function and localization, with potential applications in research areas such as cardiology, dermatology, and tissue engineering. Its specificity and sensitivity make it a valuable asset for unraveling the complex mechanisms underlying cell-cell adhesion and tissue organization.
Product Name:
Desmoplakin Rabbit Polyclonal Antibody
SKU:
CAB13299
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 2609-2830 of human Desmoplakin (NP_004406.2).
This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1832
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Desmoplakin Rabbit pAb (CAB13299) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
