The DRD5 Polyclonal Antibody (CAB1719) is a valuable tool for researchers studying the dopamine receptor D5 (DRD5) protein, which plays a crucial role in the central nervous system. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the DRD5 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it well-suited for investigations in neuroscience and pharmacology.DRD5 is a key player in dopamine signaling pathways, influencing various physiological processes such as motor control, reward, and cognition.
Dysregulation of DRD5 has been implicated in neuropsychiatric disorders like schizophrenia, ADHD, and Parkinson's disease, making it a promising target for drug development and therapeutic interventions. By elucidating the mechanisms underlying DRD5 function, researchers can uncover new insights into neurological disorders and potentially identify novel treatment strategies.
Product Name:
DRD5 Rabbit Polyclonal Antibody
SKU:
CAB1719
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 323-477 of human DRD5 (NP_000789.1).
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2.
Purification Method:
Affinity purification
Gene ID:
1816
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of U-87MG cells, using DRD5 antibody (CAB1719) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
