The DRD4 Polyclonal Antibody (CAB1337) is a valuable tool for research involving the dopamine receptor D4 (DRD4), a protein involved in neurotransmission and behavior. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the DRD4 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in neuroscience and psychology.DRD4 is known for its role in dopamine signaling and has been linked to various behavioral traits and psychiatric disorders.
Understanding the function of DRD4 is essential for unraveling the complex interplay between neurotransmitters and behavior, shedding light on conditions such as ADHD, addiction, and schizophrenia. The DRD4 Polyclonal Antibody provides researchers with a powerful tool for investigating the function and regulation of this important receptor, paving the way for new insights and potential therapeutic targets in neuropsychiatry.
Product Name:
DRD4 Rabbit Polyclonal Antibody
SKU:
CAB1337
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DRD4 (NP_000788.2).
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
Purification Method:
Affinity purification
Gene ID:
1815
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using DRD4 Rabbit pAb (CAB1337) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
