Dopamine Receptor D3 (DRD3) Rabbit Polyclonal Antibody (CAB1556)
- SKU:
- CAB1556
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Dopamine Receptor D3 (DRD3) Rabbit Polyclonal Antibody |
SKU: | CAB1556 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 213-329 of human Dopamine Receptor D3 (Dopamine Receptor D3 (DRD3)) (NP_000787.2). |
Sequence: | VVLK QRRR KRIL TRQN SQCN SVRP GFPQ QTLS PDPA HLEL KRYY SICQ DTAL GGPG FQER GGEL KREE KTRN SLSP TIAP KLSL EVRK LSNG RLST SLKL GPLQ PRGV PLRE KKAT Q |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | D3DR; ETM1; FET1; Dopamine Receptor D3 (DRD3) |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Multi-pass membrane protein. |
Calculated MW: | 44kDa |
Observed MW: | 44kDa |
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Purification Method: | Affinity purification |
Gene ID: | 1814 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |