The DRD3 Polyclonal Antibody (CAB1556) is a valuable tool for researchers studying the dopamine receptor D3 (DRD3) protein. This antibody, produced in rabbits, is highly sensitive and specifically recognizes human samples, making it suitable for a variety of applications, including Western blotting.The DRD3 protein is a G protein-coupled receptor that plays a crucial role in dopamine signaling in the brain. Dysregulation of DRD3 has been implicated in various neurological and psychiatric disorders, including schizophrenia and addiction.
By targeting the DRD3 protein, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets.With its high reactivity and specificity, the DRD3 Polyclonal Antibody (CAB1556) is an essential tool for investigating the role of DRD3 in health and disease. Its versatility and reliability make it an ideal choice for studies in neuroscience, pharmacology, and drug discovery.
Recombinant fusion protein containing a sequence corresponding to amino acids 213-329 of human Dopamine Receptor D3 (Dopamine Receptor D3 (DRD3)) (NP_000787.2).
This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Purification Method:
Affinity purification
Gene ID:
1814
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse brain, using Dopamine Receptor D3 (Dopamine Receptor D3 (DRD3)) antibody (CAB1556) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
